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派博传思国际中心 »期刊书目

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› BOOKS with Alphabet C (Ca, Cb,Cc, Cd, Ce…... )

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Titlebook: Camptothecins in Cancer Therapy; Val R. Adams,Thomas G. Burke Book 2005 Humana Press 2005 DNA.biochemistry.brain.brain tumors.cancer.cance

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发表于 2025-3-21 16:50:09 | 显示全部楼层 |阅读模式
书目名称Camptothecins in Cancer Therapy
编辑Val R. Adams,Thomas G. Burke
视频videohttp://file.papertrans.cn/221/220974/220974.mp4
概述Includes supplementary material:
丛书名称Cancer Drug Discovery and Development
图书封面Titlebook: Camptothecins in Cancer Therapy; Val R. Adams,Thomas G. Burke Book 2005 Humana Press 2005 DNA.biochemistry.brain.brain tumors.cancer.cance
描述A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
出版日期Book 2005
关键词DNA; biochemistry; brain; brain tumors; cancer; cancer therapy; chemistry; drug; drug delivery; drug design; l
版次1
doihttps://doi.org/10.1385/1592598668
isbn_softcover978-1-62703-816-4
isbn_ebook978-1-59259-866-3Series ISSN 2196-9906 Series E-ISSN 2196-9914
issn_series 2196-9906
copyrightHumana Press 2005
The information of publication is updating

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Neuroinflammation in Huntington’s Diseasecomplex (.). At this level, the action of CPT on TOP-I function is entirely analogous to those of several agents that inhibit the function of topoisomerase II, including 4-(9-acridinylamino)-.-(methanesulfonyl)-.-anisidine (m-AMSA), etoposide, and teniposide (.).
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Progress in Inflammation Researchstases. In addition, if benign cases are considered, approximately 36,000 brain tumors would have been diagnosed in 2002. The age- and sex-adjusted incidence of primary tumors of the CNS is estimated to be approximately 19 per 100,000 persons per year (11.8 per 100,000 for symptomatic tumors and 7.3 per 100,000 for asymptomatic tumors) (.).
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Progress in Inflammation Researchrising, leveled off to the current incidence rate of 52.4 per 100,000. Overall, the 1-year survival rates for lung cancer have increased from 34% in 1975 to 42% in 1998, mainly because of improvements in surgical techniques. However, the 5-year relative survival rate for all stages is only 15% (.).
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Camptothecins in the Treatment of Primary Brain Tumorsstases. In addition, if benign cases are considered, approximately 36,000 brain tumors would have been diagnosed in 2002. The age- and sex-adjusted incidence of primary tumors of the CNS is estimated to be approximately 19 per 100,000 persons per year (11.8 per 100,000 for symptomatic tumors and 7.3 per 100,000 for asymptomatic tumors) (.).
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