Titlebook: Brain and Mental Health in Ageing; Gurcharan Kaur,Suresh I. S. Rattan Book 2024 The Editor(s) (if applicable) and The Author(s), under exc

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Maintenance of Mitochondrial Dynamics for Healthy Brain Ageingndergoes a natural ageing process resulting in altered mitochondrial architecture and function, which is implicated in age-related neurological conditions. Mitochondria influence various biochemical processes, including ATP production, fatty acid synthesis, ROS generation, and calcium regulation; th

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Phytochemicals and Vitagenes for a Healthy Brainders. According to hormesis, phytochemicals exhibit biphasic dose response effects activating at low dose antioxidant signaling pathways resulting in upregulation of vitagenes, as in the case of the Nrf2 pathway upregulated by plant polyphenols. Interestingly, dysregulation of Nrf2 pathway can exace

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Infection, Neuroinflammation and Interventions for Healthy Brain and Longevityty of treatments. The amyloid hypothesis of the disease pathogenesis predominated during decades stating that amyloid beta (Aβ) formation and oligomerization is the major cause for AD. Recently, beside the amyloid plaques and neurofibrillary tangles, the neuroinflammation was added as a derivative o

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Nutraceuticals as an Intervention for Healthy Brain Ageingaffecting the lifestyle of the older population. The rate of brain ageing is influenced by genetics, hormones, neurotransmitters, and exposure to the environment. Over the years, methods for suppressing the signs of brain ageing and a demand for neuroprotective agents have emerged. A possible answer

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Sleep and Circadian Rhythms as Modulators of Mental Health in Ageingound 24 h. These rhythms are regulated by molecular clocks situated in the Suprachiasmatic Nucleus (SCN), synchronized with the solar day‘s light–dark cycle. The sleep–wake cycle, a prominent manifestation of circadian rhythms, plays a crucial role in mental well-being. Perturbations in sleep patter

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Gurcharan Kaur,Suresh I. S. RattanHighlights the need to redefine mental health in the context of a growing ageing global population.Focuses on the biological modulators of healthy brain ageing.Addresses the impact of multi-dimensiona