Titlebook: Bronchiectasis; The EMBARC Manual James Chalmers,Eva Polverino,Stefano Aliberti Book 2018 Springer International Publishing AG 2018 Airway

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Severity of the Disease, Site of Care and Self-Management,ions and a detrimental impact on quality of life. The cornerstone of bronchiectasis is abnormal dilation of the bronchi and this is visible on CT scanning of the thorax; however radiological assessment of bronchiectasis is not encompassing enough to fully assess severity [1]. There are patients with

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, and Bronchiectasis,s chapter, we highlight important aspects of . biology, its virulence factors and the multiple routes to antibiotic resistance including biofilm and genetic mechanisms. We also highlight clinical challenges in managing patients with persistent infection.

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The Role of Other Bacteria, Fungi, and Viruses in Bronchiectasis, the airways and the surrounding lung parenchyma [1]. Many microorganisms have been associated with bronchiectasis, both as a complication of the anatomic abnormalities and possibly as a cause of the structural disease as well [2, 3]. Diverse polymicrobial communities are present in the airways of p

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NTM in Bronchiectasis,th an increase in incidence and prevalence worldwide [1, 2]. While . (MAC) remains the most common of the NTM isolates causing lung disease throughout the world, there are geographic variations of other NTM species-specific lung disease differences at the inter- and intracontinental levels that are

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Airway Clearance in Bronchiectasis,e aims of ACT and current practices in bronchiectasis. The main physiological mechanisms underlying ACTs as well as the current evidence base are detailed. Mucoactive drugs are discussed particularly in terms of dose, delivery device/route and timing with ACT to facilitate airway clearance. Recognis

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How to Identify Causes and Predisposing Factors in Bronchiectasis,ting European data show a prevalence of bronchiectasis from 67 to 566 . 100,000, while prevalence in the USA has been estimated about 52 . 100,000 [3–6]. All these data have changed the earlier consideration of bronchiectasis as an orphan disease towards an increased awareness of this condition.

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