Titlebook: Breast MRI for High-risk Screening; Francesco Sardanelli,Franca Podo Book 2020 Springer Nature Switzerland AG 2020 Breast cancer.screening

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Gadolinium-Based Contrast Agents for Breast MRI and Uncertainties About Brain Gadolinium Retention,nly the diagnostic performance of contrast-enhanced protocols but also the expected findings on diffusion-weighted imaging (DWI) or .H magnetic resonance spectroscopy. The high-risk screening setting, potentially necessitating repeated examinations over decades, requires that a specific evaluation o

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Applying the MRI BI-RADS in a High-Risk Population,, also in high-risk women. In the general population, the application of the BI-RADS allowed for a very good diagnostic performance, although associated with rather low inter-reader agreement. This good performance was seen also for the application of the BI-RADS lexicon in screening high-risk women

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Radiogenomics and Phenotype Presentation of Breast Cancer with a Special Focus on High-Risk Women,ression profiling has revolutionized breast cancer classifications, and the traditional classifications based on immunohistochemistry have been replaced by molecular subtype profiles. Breast cancer has four distinct molecular subtypes: luminal A; luminal B; human epidermal growth factor receptor 2 (

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Primary Studies on Breast MRI Screening of High-Risk Women,t debate about its harm-to-benefit balance and the wide range of estimated overdiagnosis, associated with overtreatment. In particular, the limitations of the principle . underlying population-based screening programs is discussed, with the perspectives for more personalized approaches, based on ris

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Genetic/Familial High-Risk Screening: MRI Alone?,ening programs throughout Europe and the United States. International societies have established guidelines for these programs, which may vary from nation to nation. The combined use of mammography, ultrasonography (US), and magnetic resonance imaging (MRI) has the best diagnostic performance and yi

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Systematic Reviews, Meta-Analyses, and Cost-Effective Analyses on Breast MRI Screening of High-Riskm therapy to diagnostics. Secondary studies, that are finalized to summarize the evidence available in the published literature on a given topic, acquired a prominent role in the decision to recommend in favor or against a medical technology. These studies favored the adoption of breast MRI for scre

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