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Titlebook: Breast Diseases; Breast-Conserving Th F. Kubli,M. Bauer,H. Junkermann Conference proceedings 1989 Springer-Verlag Berlin Heidelberg 1989 St

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Introduction: In Memory of Joseph Hirsch (1876–1947)e was not too advanced. In 1927, he published his results [10] with a 13-year period of meticulous follow-up. Hirsch appears to be one of the first surgeons — if not the very first — to publish a controlled study or breast-conserving therapy in combination with radiotherapy for carcinoma of the breast.
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S Phase Fractions and DNA Ploidy as Prognostic Factors in Breast Cancer, where the terms “slow” and “fast” tend to reflect the subjective impression of the observing clinician. The biological explanation of the differences in tumor growth patterns, among other aspects of tumor aggression, is given by tumor cell cycle kinetic studies.
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Multicentricity in Breast Carcinomawith the various techniques available (quadrantectomy, wide excision, lumpectomy, and subsequent radiotherapy) has found acceptance and is being applied in an increasing number of cases [2,3,5,16,17,20,36].
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