Titlebook: Breast Disease; Management and Thera Adnan Aydiner,Abdullah Igci,Atilla Soran Book 2019Latest edition Springer Nature Switzerland AG 2019 b

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Evaluation of Patients for Metastases Prior to Primary Therapys in breast cancer patients is by patient signs and symptoms including history and physical examination, laboratory tests, imaging, biopsy of suspicious finding in imaging studies, and monitoring serum markers.

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Biopsy Techniques in Nonpalpable or Palpable Breast Lesionsassic surgical incisional and excisional biopsies. Fine-needle aspiration (FNA) has an important historical role and remains among the most cost-effective methods but is limited by the weakness of current breast cytology to adequately reproduce all information provided by traditional histopathology.

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Evaluation of Patients for Metastases Prior to Primary Therapyto axillary surgery for SLNB or ALND or to neoadjuvant chemotherapy in those with axillary node-positive disease. However, there is no perfect modality to identify metastatic disease in breast cancer; every diagnostic test has its own advantages and limitations. The available evidence suggests routi

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Breast Cancer Staging prognosis of patients with newly diagnosed breast cancer. According to the seventh revised edition of the TNM system in 2009, the presence of isolated tumor cells (ITCs) or micrometastases in axillary lymph nodes has little impact on survival. Furthermore, due to the increasing application of neoad

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Adjuvant Systemic Therapy: Endocrine Therapy5% of all breast cancers. Adjuvant endocrine therapy is a pivotal component of treatment for women with hormone receptor-positive early-stage breast cancer; it delays local and distant relapse and prolongs survival. Patients with ER- and/or PR-positive invasive breast cancers should be considered fo

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Adjuvant Systemic Chemotherapy for HER2-Negative Diseasepy. All patients with invasive breast cancer should be evaluated to assess the need for adjuvant cytotoxic therapy, trastuzumab, and/or endocrine therapy. If patients must receive endocrine therapy (either tamoxifen or aromatase inhibitor) and cytotoxic therapy as adjuvant therapy, chemotherapy shou