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Titlebook: Breast Cancer, a Heterogeneous Disease Entity; The Very Early Stage Zsuzsanna Kahán Book 2011 Springer Science+Business Media B.V. 2011 1.

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Systemic Therapy: Selection of Patients, cancers is even higher among early breast cancers. The rationale the currently applied endocrine manipulations is oestrogen deprivation, either by competitive blockade of the hormone at the level of its receptor or by inhibition of its synthesis. The automatic administration of endocrine agents to
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et.Relatively wide readership.Includes supplementary materiaThe volume raises attention to the need of a completely new approach to breast cancer based on the knowledge collected on early breast cancer in the past two decades. The chapters are contributed by experts of all the fields participating i
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Rolf Kreienberg,Volker Möbus,Thorsten Kühnf skin, the pectoral muscle or the chest wall. After the diagnosis of breast cancer, MRI is able to detect additional foci in the same or in the contralateral breast in up to 24% of the cases, which frequently results in changes in the therapy plan. MRI is also a successful imaging method for the detection of residual and recurrent disease.
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Systemic Therapy: Selection of Patients,nitive dysfunction, thus deteriorating health-related quality of life (HRQOL). An effort should be made to balance the issues relating to the risk of relapse and the extent of hormone sensitivity, and hence the expected benefit of therapy, together with the risks accompanying the endocrine therapy.
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