Titlebook: Breast Cancer; Textbook for General Umberto Veronesi (Direttore Generale) Book 1990 Springer-Verlag Berlin Heidelberg 1990 Staging.breast c

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SurgeryOne hundred years ago W.S. Halsted opened up a new era in breast cancer treatment, introducing the “radical mastectomy”. The principle of Halsted was that a rigourous, accurate surgical technique which would remove the breast “en bloc” with the pectoralis muscles and the axillary nodes would cure a considerable number of patients.

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Bernhard Felderer,Stefan Homburgdecades subsequent to 1950, breast cancer caused the deaths of nearly one million women in the United States alone. Within the 12 Member States of the European Economic Community (EEC), the number of deaths attributed to breast cancer rose from 30,695 in the mid-1950s to 60,965 per annum in the mid-1980s: almost a doubling of the cases.

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Epidemiology of Breast Cancerdecades subsequent to 1950, breast cancer caused the deaths of nearly one million women in the United States alone. Within the 12 Member States of the European Economic Community (EEC), the number of deaths attributed to breast cancer rose from 30,695 in the mid-1950s to 60,965 per annum in the mid-1980s: almost a doubling of the cases.

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Treatment of Overt Metastatic Diseaseth the available treatments should obtain the maximal relief of symptoms (possibly even start therapy just before their onset), for the maximal duration with the minimal burden of side effects. The decision to treat and the choice of treatment must therefore take into account the extent of the disea

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