Titlebook: Brainstem Tumors; Diagnosis and Manage George I. Jallo,Mohammad Hassan A. Noureldine,Nir Book 2020 Springer Nature Switzerland AG 2020 bra

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,Diffuse Midline Glioma – Diffuse Intrinsic Pontine Glioma,opulation and is associated with dismal prognosis, where less than 10% of sufferers survive beyond 2 years from diagnosis. The diagnosis was based upon the typical clinical presentation/progression and imaging features, and biopsy was discouraged at some point due to the associated surgical toxicity

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Surgery for Vascular Lesions of the Brainstem,ons, and cavernous malformations can be found in close association with all levels of the brainstem. Due to the inherent risk of treating brainstem pathologies, all surgical decision-making must first be predicated on knowledge of the natural history and radiographic appearance of these lesions. Suc

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Inflammatory and Infectious Lesions of the Brainstem, connective tissue diseases (CTDs), and vasculitis. In many cases, the underlying etiology is readily apparent, and a specific treatment can be initiated at the time of presentation. This concerns, for example, patients with known multiple sclerosis who develop symptoms or signs of BS dysfunction. W

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Surgical Approaches to Pontine Tumors,rough anatomical knowledge of the trajectory towards and the neurovascular structures surrounding the pons as well as the intrapontine architecture allows the surgeon to anticipate encountering the next critical structure that should be cautiously preserved. The anterior pontine surface can be visua

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encyclopedia

Radiation and Chemotherapy for Brainstem Tumors,ts into the biology of the most common brainstem glioma, diffuse intrinsic pontine glioma (DIPG), the standard treatment for brainstem gliomas has not changed significantly in nearly five decades. Radiation therapy is the mainstay of treatment for DIPG and other malignant brainstem gliomas, and is t

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Future Therapies for Malignant Brainstem Tumors,nfiltrative nature of the tumor and the structure of the brainstem, surgical resection is not a therapeutic option for DIPG. Radiation therapy is the current standard of care for this tumor but is only palliative. Conventional chemotherapy has not shown efficacy. Obstacles in achieving effective non

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Book 2020eaders through the depth of the complex architecture of the brainstem in the clinical context, and emphasizing the evidence-based treatment of different brainstem pathologies while also reviewing what the future holds for the management of these pathologies, the book presents a review of state-of-th

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Mesenchymal Stem Cell and Its Properties,nd assist in treatment planning. When evaluating neoplastic lesions, imaging may also serve to distinguish between neoplastic progression versus development of post-treatment changes. In this chapter, we provide an overview of the typical imaging appearance of common neoplastic and non-neoplastic le