Titlebook: Brain Iron Metabolism and CNS Diseases; Yan-Zhong Chang Book 2019 Springer Nature Singapore Pte Ltd. 2019 Iron.Iron metabolism.Brain.Neuro

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Cellular Iron Metabolism and Regulation,n the optimal physiologic range, iron metabolism at the cellular level and the whole systemic level are tightly regulated. Balance of iron homeostasis depends on the expression levels and activities of iron carriers, iron transporters, and iron regulatory and storage proteins. Divalent metal transpo

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Brain Iron Metabolism and Regulation, in the brain. Brain iron metabolism disorders might be one cause of neurodegenerative diseases. This review mainly summarizes the normal process of iron entry into the brain across the blood–brain barrier, and the distribution and transportation of iron among neurons and glial cells, as well as the

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,Iron Pathophysiology in Alzheimer’s Diseases,earance of deposit of neurofibrillary tangles. Increasing evidence suggests that disorders of metal ion metabolism in the brain are one of the risk factors for the pathogenesis of AD. Iron, one of the endogenous metal ions, involves in many important physiological activities in the brain. Iron metab

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The Role of Iron in Amyotrophic Lateral Sclerosis,, brainstem, and spinal cord. The etiology and pathogenesis of this devastating disease remain largely unknown. Increasing evidence suggests that iron accumulation is involved in the onset and progression of ALS. In this review, we discuss the regulation of iron homoeostasis in the brain, the misreg

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