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Titlebook: Brain Failure; David Bihari,John W. Holaday Conference proceedings 1989 Springer-Verlag Berlin Heidelberg 1989 Nervous System.Sepsis.Traum

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Encephalopathy Associated with Liver Disease, with a lack of response to painful stimuli. The degree to which symptoms of encephalopathy are seen within an individual patient appears to be directly related to the speed of development of the hepatic failure; thus a paracetamol overdose may proceed from mild disorientation to grade IV coma over the course of several hours.
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Pathophysiology and Treatment of Stroke,e available, which can be strongly recommended [1, 2]. The goal of the present chapter, which of necessity must be more modest, will be to focus upon the topic of completed stroke of ischemic origin and to emphasize primarily
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Neurotoxic Amino Acids and Amino Acid Antagonists as Neuroprotective Agents,ology arising from the ischemic insult are complex and a number have been considered. Over the past few years evidence has accumulated to suggest a fundamental involvement of excitatory amino acids. Glutamate and aspartate are widely acknowledged as the major excitatory transmitters in the mammalian
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The Role of Lipid Peroxidation in Ischemic Central Nervous System Injury,nitiation of lipid peroxidation and the role of iron in this event. An answer to these issues will depend on the advent of more precise and improved methods of measurement. Until then, evidence to support lipid peroxidation as a mediator of tissue injury will rely largely on current methods of detec
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Anaerobic Metabolism Within the Brain: Its Relationship to Brain Failure in Head-Injured Patients,ardiac arrest, oxygen supplies are depleted within 30s. Oxidative phosphorylation ceases, but endogenous stores of glucose maintain anaerobic glycolysis for a few moments. The amount of lactic acid accumulation is primarily dependent upon the preischemia tissue glucose stores, which are proportional
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Pathophysiology of the Encephalopathies Associated with Uremia and Hyponatremia, patients continue to manifest a variety of neurologic disorders [1]. Patients with chronic renal failure who have not yet received dialytic therapy may develop symptoms ranging from mild sensorial clouding to delirium and coma [2]. Even after the institution of adequate maintenance dialysis therapy
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Encephalopathy Associated with Liver Disease, with a lack of response to painful stimuli. The degree to which symptoms of encephalopathy are seen within an individual patient appears to be directly related to the speed of development of the hepatic failure; thus a paracetamol overdose may proceed from mild disorientation to grade IV coma over
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