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Titlebook: Bone Scanning in Clinical Practice; Ignac Fogelman (Consultant Physician) Book 1987 Springer-Verlag Berlin Heidelberg 1987 bone.imaging.nu

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发表于 2025-3-21 17:11:51 | 显示全部楼层 |阅读模式
期刊全称Bone Scanning in Clinical Practice
影响因子2023Ignac Fogelman (Consultant Physician)
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图书封面Titlebook: Bone Scanning in Clinical Practice; Ignac Fogelman (Consultant Physician) Book 1987 Springer-Verlag Berlin Heidelberg 1987 bone.imaging.nu
影响因子The most frequently requested investigation in any nuclear medicine department remains the technetium-99m (99mTc)-labelled diphosphonate bone scan. Despite rapid advances in all imaging modalities. there has been no serious challenge to the role of bone scanning in the evaluation of the skeleton. The main reason for this is the exquisite sensitivity of the bone scan for lesion detection. combined with clear visualisation of the whole skeleton. In recent years several new diphosphonate agents have become available with claims for superior imaging of the skeleton. Essentially. they all have higher affinity for bone. thus allowing the normal skeleton to be visualised all the more clearly. However. as will be dis­ cussed. this may occur at some cost to the principal role of bone scanning. lesion detection. The major strength of nuclear medicine is its ability to provide functional and physiological information. With bone scanning this leads to high sensitivity for focal disease if there has been any disturbance of skeletal metabolism. However. in many other clinical situations. and particularly in metabolic bone disease. more generalised alteration in skeletal turnover may occur. and q
Pindex Book 1987
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Intelligent Systems Reference Librarysuch as heterotopic ossification and soft tissue calcification. The requirements of an ideal bonescanning agent are excellent imaging properties of the nuclide, high concentration of the nuclide at the abnormal site, little or no extraosseous or noncalcification site uptake, minimum tissue radiation
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Intelligent Systems Reference Librarywhich purpose the entire skeleton should be imaged. For other purposes it is often adequate to examine only part of the skeleton. The amount of isotope taken up at any site depends primarily on the local rate of bone turnover rather than on bone mass. The scintigraphic appearance therefore does not
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Secret Buddhas, the Veiled Presence,ent of .Tc-labelled polyphosphate by Subramanian and McAfee in 1971. This important advance meant that a compound with high skeletal affinity could at last be combined with a radionuclide with nearideal physical properties. Nevertheless, there was a continuing search for further improvement and seve
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