Titlebook: Bone Morphogenetic Proteins: Systems Biology Regulators; Slobodan Vukicevic,Kuber T. Sampath Book 2017 Springer International Publishing A

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BMP Signaling in Fibrodysplasia Ossificans Progressiva, a Rare Genetic Disorder of Heterotopic Ossin underlying cellular mechanism for HO. The identification of the responsible gene for FOP, together with the development of animal models for HO and FOP, is now leading to advances in understanding the cellular and molecular mechanisms of bone formation and the induction of HO.

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The Central Role of BMP Signaling in Regulating Iron Homeostasis,hat must be exquisitely controlled to prevent the pathologic states of iron excess or iron deficiency. BMP signaling in the liver by the BMP ligands and receptors including the co-receptor hemojuvelin/RGMc regulates the expression of the iron hormone hepcidin to maintain iron homeostasis.

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Book 2017function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-bet

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BMPs in Dental Medicine: Promises and Challenges, recombinant human BMP-2 (rhBMP-2) but also recombinant human BMP-7 (rhBMP-7) and recombinant human growth/differentiation factor-5 (rhGDF-5) in craniofacial settings to include alveolar bone augmentation for implant dentistry.

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