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Titlebook: Bone Metastases; Diagnosis and Treatm R. D. Rubens (Professor),I. Fogelman (Consultant P Book 1991 Springer-Verlag London Limited 1991 bone

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Assessment of Response to Treatment, improvement. Control of the tumour by systemic therapy reduces osteoclast activity allowing bone healing, mediated by osteoblasts, to occur. However, as assessment of response for most tumours is based on changes seen on serial plain radiographs, the precise effect of therapy is difficult to measur
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Isotope Therapy For Bone Metastases,ule to target radiotherapy to a tumour has been well established with the use of iodine-131 in the treatment of follicular thyroid cancer and phosphorus-32 to treat polycythaemia rubra vera (Seidlin et al. 1946; O’Mara 1978).
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Symptomatic and Supportive Care,ead will also be present in patients who have bone metastases. In this chapter, however, the main focus will be on those symptoms more particularly caused by the bone involvement itself such as bone pain, poor mobility or anaemia, and the psychological support needed by such patients.
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Book 1991ology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care. Particularly new approaches included are magnetic resonance imaging, the assessment of skeletal response and isotope therapy.
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R. D. Rubens (Professor),I. Fogelman (Consultant P
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