Titlebook: Bone Metastases; Medical, Surgical an Dominique G. Poitout (Prof. Chief of Dept.) Book 2002 Springer-Verlag London 2002 bone metastases.bon

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BiphosphonatesThe biphosphonates have a phosphate-carbon-phosphate backbone, which binds tightly to calcified bone matrix. This core structure allows many possible variations by changing side chains or by esterifiyng phosphate groups. Many biphosphonates have been synthesised, with different chemical and biological characteristics.

sterilization

Hormonal TherapyBone lesions are the most common sites of metastasis for prostate and breast carcinoma, and may also occasionally result from endometrial carcinoma.

Condyle

Cement-Containing AntimitoticsBuchholz and Hengelbrecht were the first to use cement as a vehicle for active drug substances when, in 1970, they combined gentamicin with Palacos cement. This combination with gentamicin was found to be stable and able to provide effective antibiotic activity against the main pathogens encountered in bone surgery.

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Treatment of Secondary Spinal TumoursThe diagnosis and treatment of spinal metastatic tumours is an increasing part of an orthopaedic spinal surgeon’s role, as the life expectancy of patients with treatable malignancy increases.

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amenity

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cancellous-bone

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