Titlebook: Bone Marrow Transplantation; Basic and Clinical S Susumu Ikehara (Professor),Fumimaro Takaku (Presid Conference proceedings 1996 Springer-V

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Roles of Jak Kinases in Human GM-CSF Receptorlinking and immunoprecipitation revealed that the α and β subunits associate following stimulation with GM-CSF, but the β subunit forms a homodimer even in the absence of the ligand. We analyzed the mechanism of . mRNA activation by GM-CSF using several hGMRβ subunit mutants. In addition to boxl reg

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Fibronectin Rescues Bone Marrow Cells from Apoptosis with IgGfter depletion of IL-3. However, addition of fibronectin with normal IgG rescued the cells from apoptosis by an autocrine mechanism of IL-3. However neither fibronectin alone nor IgG alone induced IL-3. Addition of either RDG peptide or anti-integrin VLA-4 or anti FcγRIII mAb 2.4G2 blocked IL-3 indu

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Development of Blood Cells from Mouse Embryonic Stem Cells in Culturetopoiesis in lethally irradiated mice during the differentiation induction. Several systems of . differentiation induction from ES cells to lympho-hematopoietic cells are summarized. The usefulness and the limitation of the . differentiation induction systems are discussed.