| 期刊全称 | Bone Marrow Niche | | 期刊简称 | Microenvironments Cr | | 影响因子2023 | Takashi Nagasawa | | 视频video | | | 发行地址 | Illustrates the complete organization of complex bone marrow microenvironments.Explains how mesenchymal cells maintain and regulate hematopoietic stem and progenitor cells.Provides a unique perspectiv | | 学科分类 | Current Topics in Microbiology and Immunology | | 图书封面 |  | | 影响因子 | .This volume summarizes recent advances in research on mesenchymal cell populations in the bone marrow. It explores how mesenchymal cells create niches for immune cells in extramedullary organs and it discusses new concepts of lympho-hematopoietic microenvironments. Readers are introduced to the fundamentals of hematopoietic stem cells (HSCs) differentiation to all types of blood cells, including immune cells, in the bone marrow. The book highlights how this process is supported and regulated by the individual microenvironments of stem cells, termed niches..The identity of HSC niches has been subject to longstanding debates. Recent studies identified the population of mesenchymal stem cells as the major cellular component of niches, for hematopoietic stem and progenitor cells (HSPCs) and their candidate developmental origin. Furthermore, candidate cellular niches for immune cells in lymph nodes and adipose and connective tissues were identified. The authors of this volumefocus on shared features between those and HSPC niche cells in the bone marrow.. .Covering latest research results, this book serves as fascinating read for researchers and clinicians in hematology and immunology.. | | Pindex | Book 2021 |
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发表于 2025-3-21 18:32:30
