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Titlebook: Bluetongue Viruses; Polly Roy,Barry M. Gorman Conference proceedings 1990 The Editor(s) (if applicable) and The Author(s), under exclusive

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https://doi.org/10.1007/978-3-031-68682-5 hosts, sheep and cattle. Additional studies have been done on murine species for the purpose of developing monoclonal antibodies and as a potential model system for elucidation of protective immune responses. Taken together, these studies have adequately identified VP2 as the primary, and possibly
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The Bluetongue Viruses,logist, Francois de Vaillant, who travelled in the Cape of Good Hope between 1781 and 1784. Although clinical aspects of the disease were recorded by ., the Chief Veterinary Officer of the Cape Colony, in his Annual Report for 1880, it was not until 1902 that “Malarial Catarrhal Fever” was first reported in the scientific literature (. 1902).
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Bluetongue Virus Structural Components, . and . 1985; . et al. 1984). The main features can be summarized as follows: BTV is an icosahedral-shaped particle consisting of a segmented double-stranded RNA genome encapsidated in a double-layered protein coat. Removal of the outer protein layer activates a viral-associated RNA polymerase whic
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The Replication of Bluetongue Virus,others in the late 1960s and continuing to the present (see Chap. 2, this volume) on the double-stranded, segmented genomic RNA (. 1969; . et al. 1970), the bishelled nature of the virus particle (. et al. 1972), the activation of the virion-bound transcriptase, and the activity of this enzyme in vi
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The Replication of Bluetongue Virus in , Vectors,1944) in South Africa was the first to implicate a . species in the transmission of this virus when he showed that . (.) was able to transmit bluetongue from infected to susceptible sheep. Since that time numerous authors have confirmed his observations (. and . 1971; . and . 1973; . et al. 1981, 19
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https://doi.org/10.1007/978-3-031-68682-5e remaining species of . may eventually be shown to be fully competent BTV vectors most species will be refractory to infection. Why this should be is not yet entirely clear, but it is known that the mechanism or mechanisms controlling the oral infection of . with BTV operate chiefly at the level of
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