Titlebook: Blood Cell Biochemistry Volume 3; Lymphocytes and Gran J. R. Harris Book 1991 Springer Science+Business Media New York 1991 Organelle.bioch

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Lymphocyte-Mediated Cytolysis Role of Granule Mediators,irus-infected and transformed cells (reviewed in Berke, 1983; Herberman .., 1986; Trinchieri and Perussia, 1984; Goldfarb, 1986). Killing by lymphocytes is known to require a contact-dependent mechanism. Although the precise mechanisms by which lymphocytes kill their targets are still unclear, a lar

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,CR1—Cytoskeleton Interactions in Neutrophils,and has several important immunologic functions (see reviews in Fearon, 1985, Schreiber, 1984, and Arnaout and Colten, 1984). For example, aside from mediating attachment of phagocytic cells to opsonized targets, erythrocyte CR1 may function in systemic clearance of complement-containing immune comp

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The Flow of Granular Organelles in Leukocyte Differentiation,e bedside. Those careful and insightful clinical observations, unfolding with the suspense of a great mystery novel, have stimulated many of the basic advances in the field. From their studies on families with premature heart disease and abnormal lipoproteins, Brown, Goldstein, and co-workers expand

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The Elusive Oxidase The Respiratory Burst Oxidase of Human Phagocytes,range of weapons in the name of host defense, they circulate vigilantly, waiting at short notice to swarm into infected tissues to assault and eliminate invading microorganisms. For over three decades, the generation of reactive oxidants by stimulated phagocytic cells has been recognized as one of t

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Myeloperoxidase: Localization, Structure, and Function,n addition, it exerts a wide variety of extracellular functions. Polymorphonuclear leukocytes (PMN) are the main source of this enzyme. MPO is a myeloid cell-specific enzyme whose synthesis is tightly regulated at the promyelocyte stage of differentiation of myeloid cells. This review will consider

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Intergenerational Learning and Dementia, is possible to begin to identify subsets of patients within histologically defined subgroups of leukemias and lymphomas that demonstrate unique clinical presentations, disease courses, and responses to therapy.

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Judith Gottschalk,Nicolai Winther-Nielsention and differentiation into antibody-secreting plasma cells or, alternatively, it may stimulate expression of only a limited set of genes (Cambier and Ransom, 1987; DeFranco, 1987; Finkelman .., 1986).

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