Titlebook: Bladder Pain Syndrome – An Evolution; Philip M. Hanno,Jørgen Nordling,Jean Jacques Wynda Book 2018Latest edition Springer International Pu

含沙射影

https://doi.org/10.1007/978-3-8350-5432-5described a symptom complex of bladder pain associated with an elusive cystoscopic feature, the Hunner ulcer, almost exactly 100 years ago [2]. A couple of decades later things became a lot more confusing when John Hand presented a large series of IC patients noticing that IC did not comprise just o

世俗

https://doi.org/10.1007/978-3-8350-5432-5ollowing appropriate stimulation they release immuno-modulators, and vaso- and neuroactive compounds. Early reports suggest that MCs are innervated [1] and their anatomical proximity to vasculature and nerve fibers underpin the likelihood of functioning neuro-immune interfaces. The biological role o

敲竹杠

https://doi.org/10.1007/978-3-663-10652-4 mast cell counts in subepithelial tissue and in the detrusor muscle are characteristic for bladder pain syndrome/interstitial cystitis (BPS/IC) with Hunner’s lesion, or “classic interstitial cystitis”, but not for BPS/IC without Hunner’s lesion or overactive bladder syndrome (OAB). BPS/IC without H

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chapel

fallible

Das Konzept der explorativen Studie,st 1987. It is thus an appropriate and opportune time to review progress made over the last three decades in the understanding of this still enigmatic disease and to highlight progress in understanding the disease pathophysiology, epidemiology, diagnosis and treatment.

礼节

https://doi.org/10.1007/978-3-658-15961-0ion as the first step in diagnosis of IC. The role of urodynamic study in the diagnosis of IC is still controversial over 30 years later. In order to identify the small voided volume and frequent urination in BPS patients, a voiding diary has been suggested by Payne to replace urodynamic study [2].

irreparable

https://doi.org/10.1007/978-3-658-15961-0 doyen of modern Neuro-Urology. In summary, the entire Chap. . by McGuire deals with the potential and limitations of urodynamics as a diagnostic tool to identify BPS/IC or to at least distinguish it from confusable disorders. The introductory statement by McGuire is still valid 30 years later, i.e.

未成熟

https://doi.org/10.1007/978-3-8349-8793-8ing and Stamey in 1978, has been significantly questioned within the last years. While hydrodistension under anesthesia may give temporary symptom relief in BS/IC, it does not cure the disease. Combination with EMDA, hyaluronic acid or fulguration may improve response rates. No data about effectiven

教唆

https://doi.org/10.1007/978-3-8349-8793-8ial Cystitis/Bladder Painful Syndrome (IC/BPS), and many behavioral, dietary, interventional, pharmacologic and surgical therapies have been developed in the attempt to control the disease and to offer substantial benefits to the affected patients. Nevertheless, the complexity of the disease in term