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Titlebook: Biotechnology in blood transfusion; Proceedings of the T C. Th. Smit Sibinga,P. C. Das,L. R. Overby Conference proceedings 1988 Kluwer Acad

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Molecular Genetic Analysis of HLA Class II Polymorphisms, composed of an alpha and a beta chain. Each individual has at least 7 beta genes and 6 alpha genes (some of which are non-functional) clustered together on chromosome 6 (Fig. 1). These genes are highly related to one another. Most of these HLA class II genes are polymorphic, having multiple allel
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The Characterization of Monoclonal Antibodies Directed against Carbohydrate Epitopes by Immunochemic1]. The possibility to determine the fine specificity of these antibodies and the increasing knowledge about the importance of carbohycrate antigens as markers in cell differentiation and in carcinogenesis [2,3] have made many of these MABs even more important as diagnostic tools in immuno-histology
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Biochemistry of HLA-B27 in Transfected Cells and Transgenic Miceells. We have isolated the genes encoding the HLA-B27k and -B27w proteins [1]. A number of diseases are associated with certain HLA alleles. Of these associations, the one linking the HLA-B27 alleles with ankylosing spondylitis is the most pronounced. Several models have been presented over the past
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Monoclonal Antibodies in Blood Coagulation involved in hemostasis. Table I lists some of these together with selected references. In the main, these reagents were developed in research laboratories as tools for the investigation of molecular structure and function. The availability of commercial reagents or MAB-based assay kits is still in
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