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Titlebook: Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook; R. Bartl,B. Frisch Book 1993 R. Bartl and B. Frisch 1993 Internal medicine.b

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Necrosis, grafts and healing in bone,tic bone death is called ., which may be associated with various factors.. This also occurs mostly in the femur, although the humerus, tibia and radius may likewise be affected. However, bone necrosis is rarely observed in the iliac crest, probably due to its abundant blood supply. Furthermore, oste
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Osteogenesis imperfecta,nd function of collagen.. The overall incidence of osteogenesis imperfecta is between 1:20000 and 1:50000 of the population.. The disorder may affect different types of collagen, and so usually presents as a generalized connective tissue disease involving bone, tendon, ligament, dentin, skin, sclera
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Osteosclerosis,ncrease in density the affected bones are more fragile. Osteosclerosis is caused by increased bone formation, reduced bone resorption or both, and may be either inherited or acquired.. The osteoscleroses may be local, multifocal or generalized, and result from a variety of metabolic, inflammatory, t
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Osteomalacia,mineralization is increased, generally by more than 100 days. Histomorphometrically, this results in a high osteoid volume greater than 10% of the total bone volume. Because the rate of bone turnover is greater in trabecular bone, the most prominent manifestation in osteomalacia occurs along the tra
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Primary hyperparathyroidism,t 3% of patients screened were found to have plasma calcium values greater than 2.6 mmol/l. Although hypercalcaemia can be caused by a wide spectrum of conditions, the vast majority of cases are due to one of two disorders: primary hyperparathyroidism and malignancy. The former occurs more frequentl
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Renal bone disease, of bone are seen mainly in patients suffering from chronic renal failure (impaired glomerular filtration rate, GFR). Variants of metabolic bone disease may also occur in patients with a normal GFR, but with renal tubular acidosis, nephrotic syndrome, renal stone diseases and oxalosis. A wide spectr
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Systemic mastocytosis,ding histamine, serotonin, heparin, prostaglandins and proteoglycans (Fig. 16.S1).. The mature mast cell has a variable contour, round, oval or spindle-shaped, and the morphological variations may reflect diverse functional states.. In the bone marrow, mast cells are primarily located adjacent to bl
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