Titlebook: Biopsy Pathology of Melanocytic Disorders; W. J. Mooi,T. Krausz Book 1992 W.J. Mooi and T. Krausz 1992 biopsy.medicine.pathology

思考才皱眉

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修饰语

Cutaneous Pigmented lesions not related to melanocytic naevi,lesions unrelated to these entities. We shall restrict ourselves largely to lesions in which increased melanin production is an essential and sometimes striking feature; the large variety of cutaneous lesions which may show only slight increase in pigmentation of the epidermal basal layer, or which

和平

Common acquired melanocytic naevi, they are usually absent at birth and emerge during childhood and puberty, to become most numerous in early adulthood. Subsequently, their numbers gradually diminish, so that they are again rare in old age (Nicholls, 1973; Cooke .., 1985; MacKie .., 1985). In the study of MacKie and colleagues (1985

Coeval

Cutaneous blue naevi and related lesions, In contrast to common acquired naevi, blue naevi are thought to originate within the dermis rather than the epidermis; a migratory arrest of melanocytes travelling from the neural crest to the epidermis has been postulated by some (Levene, 1980). However, the occurrence of naevi combining the histo

结构

Congenital melanocytic naevi,apparent in early infancy rather than at birth (Kopf .., 1985a). When compared to acquired naevi, congenital naevi are usually larger, are more frequently centred around cutaneous adnexae, more often penetrate the reticular dermis, sometimes exhibit more complex differentiation, e.g. a greater degre

有组织

Spitz naevus, desmoplastic Spitz naevus and pigmented spindle cell naevus,n about possible hormonal influences to account for this. However, Spitz (1948) demonstrated that there were major histological differences between these childhood lesions, previously erroneously diagnosed as melanomas, and true metastasizing melanomas. Subsequently it became apparent that similar ‘

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