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Titlebook: Bioprobes; Biochemical Tools fo Hiroyuki Osada Book 2017Latest edition Springer Japan KK 2017 Natural products.Chemical biology.Small molec

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Hiroyuki OsadaPresents the most advanced research using bioprobes.Summarizes the data of highlighted bioprobes such as chemical structure, origin, function, and references.Enriches basic understanding of bioprobes
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Regulatory and Policy Reforms in Japanot only for biochemical research but also for the source of drug candidates with diverse activities. Historically, microbial metabolites have been quite useful not only as medicines but also as bioprobes. As a typical example, penicillin was originally discovered as a therapeutic agent against bacte
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https://doi.org/10.1007/978-981-19-3834-4nal and internal stimuli and determine cell fate accordingly. When one or more of these strict control systems are impaired, cells begin to grow disorderly and become malignant. Even in normal development, these systems regulate the capacity for differentiation—i.e., pluripotency—and modulate cell d
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Regulatory and Policy Reforms in Japana heritable system that changes the phenotype without changing the genotype. Although the cells that constitute the various organs contain identical genomic DNA sequences, they establish and maintain different terminal phenotypes. This nongenetic cellular memory is based on epigenetics. Epigenetic i
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https://doi.org/10.1007/978-981-16-6340-6nd parasites. In adaptive immunity, T cells and B cells induce immune responses through their respective antigen receptors, called T-cell receptors and B-cell receptors, both of which specifically recognize antigens or antigenic peptides derived from microbial pathogens. In innate immunity, germline
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Book 2017Latest editioninvestigate cell functions. The information on bioprobes and their use in research makes this booka valuable source for researchers in diverse fields. Not only scientists in academia but also in the pharmaceutical industries will discover the most important information about small molecules useful f
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Regulatory and Policy Reforms in Japanly to protein. However, some tumor viruses transcribe DNA from RNA by reverse transcriptase which is RNA-dependent DNA polymerase [4, 5]. Specific inhibitors of DNA and RNA synthesis were used to prove the template of the polymerase.
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