Titlebook: Biophysics and the Challenges of Emerging Threats; Joseph D. Puglisi Conference proceedings 2009 Springer Science+Business Media B.V. 2009

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https://doi.org/10.1007/978-1-4614-7780-8ence applications. Current approaches to improving dye performance involve the addition of enzymatic oxygen scavenging systems and small molecule additives. We present an enzymatic oxygen scavenging system that improves dye stability in single-molecule experiments. Compared to the currently-employed

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Ofir Cohen,Uri Gophna Ph.D.,Tal Pupkoed to identify intermolecular NOEs between labeled proteins and unlabeled peptides and/or drug ligands, while omitting signal from intramolecular NOEs within both labeled and unlabeled constituents. The protein—peptide complex chosen to illustrate the value of such techniques is the C-terminal domai

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A Simple Model for Protein Folding,odel residues can adopt two microscopic states corresponding to the native and non-native conformations. In order to exactly enumerate the large number of possible configurations, structure is considered to grow as continuous sequences of native residues, with no more than two sequences in each mole

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,Complementarity of Hydrophobic/Hydrophilic Properties In Protein—Ligand Complexes: A New Tool to Imof molecular details of protein functioning and in drug design. Here, a brief review of docking methods is given and recent advances in improvement of their accuracy and efficiency are discussed. Two acute problems of standard docking algorithms are considered: proper ranking of putative docking sol

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Structures of Cvnh Family Lectins, proteins so far exhibit a fold that matches the unique fold of the cyanobacterial protein. The CVNH domain is a versatile protein module, and, with some exceptions, comprises 101–150 aa with two sequential repeats of 50 amino acids. We determined high resolution structures of CVNHs from ., and ., r

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The Diversity of Nuclear Magnetic Resonance Spectroscopy,ably versatile research tool. One could oversimplify NMR spectros-copy by categorizing it into the two broad applications of structure elucidation of molecules (associated with chemistry and biology) and imaging (associated with medicine). But, this certainly does not do NMR spectroscopy justice in

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