Titlebook: Biophysics and Structure to Counter Threats and Challenges; Joseph D. Puglisi,Manolia V. Margaris Conference proceedings 2013 Springer Sci

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Macromolecular Models by Single Molecule FRET,e attached, a three-dimensional model of the system can be determined by docking calculations. Here we discuss recent applications of single molecule FRET to obtain a model of the synaptotagmin-1:SNARE complex and to study the conformation of PSD-95.

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1874-6500 that multifaceted approaches and new technologies are needed to solve the biological challenges of our time.  The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease. .978-94-007-4925-2978-94-007-4923-8Series ISSN 1874-6500 Series E-ISSN 1874-6535

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Course Abstracts,loidogenic disease formation. We also crystallized Nb484 alone and collected a complete dataset at high resolution (1.2 Å). Our experiments suggest that the nanobodies can be used as a molecular tool by helping the crystallization and by inhibiting the PrP. to PrP. transition.

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Biophysics and Structure to Counter Threats and Challenges

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https://doi.org/10.1007/978-3-031-38813-2f fluorescent dyes at specific sites in the macromolecule. Multiple such experiments can be performed with different labeling site combinations in order to map complex conformational changes or interactions between multiple molecules. Distances that are derived from such experiments can be used for