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Titlebook: Biophysical Characterization of Functional Peptides; Vibin Ramakrishnan Book 2023 The Editor(s) (if applicable) and The Author(s), under e

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Giovanni Olivi,Roeland De Moor,Enrico DiVitoe to their similarity to the host‘s extracellular matrix. It has high water content, relatively high biocompatibility, and self-healing properties. It can also be used as a heterogeneous catalyst for industrial applications. Hence, it is crucial to determine the rheological properties of hydrogels t
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Giovanni Olivi,Roeland De Moor,Enrico DiVitorm encephalopathy. The formation of amyloid fibrils from disordered peptides occurs through a nuclei dependent polymerization pathway characterized by the slow nucleation phase followed by the rapid oligomerization and fibril formation; also called the elongation phase. More recently, they have also
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J. Donnez,M. Nisolle,F. Casanas-Rouxd fibrils formation is considered a hallmark for detecting Alzheimer’s disease (AD). Anomalous multiplications of the A. precursor protein (APP) gene and mutation of the APP gene lead to AD. Understanding the amyloid formation mechanism could help us design new technologies and methods for its preve
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Giovanni Olivi,Roeland De Moor,Enrico DiVitodetails different biophysical techniques such as fluorescence spectroscopy, circular dichroism, Fourier transform infrared spectroscopy, dynamic, static light scattering and transmission electron microscopy to characterize Aβ. nucleation, aggregation, and fibrillization.
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Estimation of Aggregation Kinetics,details different biophysical techniques such as fluorescence spectroscopy, circular dichroism, Fourier transform infrared spectroscopy, dynamic, static light scattering and transmission electron microscopy to characterize Aβ. nucleation, aggregation, and fibrillization.
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De Novo Peptide Design Tools,ent programs that can be used independently or together as a pipeline for the design and computational characterization of peptides. The toolkit includes programs for checking the chirality of amino acids (ProChiral), generating contact maps (CoMa), analyzing data redundancy (DaRe), calculating the
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