Titlebook: Biopharmaceutical Manufacturing; Progress, Trends and Ralf Pörtner Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusi

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Biopharma 4.0: Digital Technologies Driving Smart Manufacturingbiopharma industry has embraced this new paradigm in response to the challenges posed by the COVID-19 pandemic. The Biopharma 4.0 transformation is being driven by three categories of forces: market forces, advancements in life science technologies, and the digital technology revolution. The market

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Towards a Continuous Production of Human Mesenchymal Stromal Cells in a Chemically Defined Medium: Oes focus more and more on juvenile hMSCs (e.g. isolated from the umbilical cord) as these show unique therapeutic properties. For their therapeutic application, a complex manufacturing process is required to produce the high hMSC yield in the therapeutic quality as it is need for the indication. Thi

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Manufacturing and Quality of Advanced Therapeutics: Cellular Therapies, CAR-T and Gene Therapies.Common to all facets of advanced therapies is that the active pharmaceutical ingredients are vastly more complex than those of common biologics such as antibodies and hence pose elevated challenges regarding their manufacture and quality control..We discuss prominent examples of advanced therapies

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https://doi.org/10.1007/978-3-031-45669-5biopharmaceuticals; therapeutic antibodies; manufacturing; viral vaccines; gene and cell therapy; up- and

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Biopharmaceutical Manufacturing978-3-031-45669-5Series ISSN 1389-6946 Series E-ISSN 2542-9515

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Ralf PörtnerComprehensive review of manufacturing aspects for biopharmaceuticals, including cell and gene therapy.Brings together the knowledge and experience of leading international experts from academia and in

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Cell Engineeringhttp://image.papertrans.cn/b/image/188317.jpg