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Titlebook: Bioorganic Chemistry of Biological Signal Transduction; Herbert Waldmann Book 2001 Springer-Verlag Berlin Heidelberg 2001 Bioorganic Chemi

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Modelling of Pulsed-Laser Ablationa putative model for mammalian PC-PLCs. The similarity of the active site of PLC. with other phosphoryl transfer enzymes has also served as a stimulus for mechanistic studies. The present account details recent studies of this important member of the PLC superfamily of enzymes.
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Bioorganic Chemistry of Biological Signal Transduction
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https://doi.org/10.1007/978-3-662-03253-4of the iterative optimization cycles revealing new peptidomimetic and non-peptide SH2 domain antagonists. Finally, an outlook is given on further applications of the modular chemistry concept and the privileged building blocks, that have been developed in SH2 domain inhibitor programs, onto a new class of adaptor proteins, notably the PTB domains.
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