Titlebook: Biomedical Engineering Technologies; Volume 1 Miguel R. Ossandon,Houston Baker,Avraham Rasooly Book 2022 Springer Science+Business Media, L

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A Compact Surface Plasmon Resonance Biosensor for Sensitive Detection of Exosomal Proteins for Cance biosensor (25 cm × 10 cm × 25 cm) for the detection of exosomal proteins. We have demonstrated the potential application of the compact SPR biosensor in lung cancer diagnosis using exosomal epidermal growth factor receptor (EGFR) and programmed death-ligand 1 (PD-L1) as biomarkers. The compact SPR

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Azimuthal Beam Scanning Microscope Design and Implementation for Axial Localization with Scanning Antechnique with nanometer-scale precision that requires similar instrumentation to TIRF microscopy. For robust SAIM localization, laser excitation with a homogeneous profile over a range of polar angles is required. We have applied the circle scanning principle to SAIM, constructing an optimized inst

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DNA Genotyping Based on Isothermal Amplification and Colorimetric Detection by Consumer Electronics tric dyer and a microfluidic chamber chip. In both approaches, devices are employed for chip scanning..A representative application to the genotyping of a clinically relevant SNP from human samples is provided, showing the excellent features achieved. Consumer electronic devices are able to register

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Evaluation of Tumor Development Using Hemoglobin Saturation Profile on Rodent Dorsal Window ChamberbSat profile to predict new development of new tumor areas over time. We included, in this chapter, step by step examples of the imaging processing method to obtain pixel level HbSat values from raw pixels data, the computational method to determine the HbSat profile, and the steps for the classific

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An Ultracompact Real-Time Fluorescence Loop-Mediated Isothermal Amplification (LAMP) Analyzerficantly reduced compared to the commercial benchtop real-time machine and other existing POC platforms. As a platform technology, self-sustainable, portable, low-cost, and easy-to-use analyzer design should create a new paradigm of molecular diagnosis toward a variety of infectious diseases at the

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Sample-to-Answer Microfluidic Nucleic Acid Testing (NAT) on Lab-on-a-Disc for Malaria Detection at Psing four samples simultaneously with 40 min turnaround time. It achieves a detection limit of ~0.5 parasites/μl for whole blood, sufficient for detecting asymptomatic parasite carriers. The assay is performed with an automated device described in Chapter .. The combination of sensitivity, specifici

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John DeCarlo,Michael J. Jenkins aptasensor is carried out in the presence of myoglobin (Myb), hemoglobin (Hb), and bovine serum albumin (BSA). Limit of detection (LOD) and limit of quantification (LOQ) values are 1.5 ng mL. and 5.2 ng mL., respectively. DNA-Apt SPR aptasensor performance for APC detection is also examined in artificial plasma.