Titlebook: Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric S; Jaroslav Sebestik,Milan Reinis,Jan J

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Dendrimers and Solubilitys solubility enhancers for many drugs, such as anticancer drugs, antidepressants, antifungal drugs, antihemorrhagic drugs, antihistaminics, anti-inflammatory drugs, and antimicrobial drugs, is discussed. Solubility is in close relation with delivery, bioavailability, and/or cell membrane permeability; therefore see also these chapters.

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d physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.978-3-7091-1703-3978-3-7091-1206-9

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https://doi.org/10.1007/978-1-4302-1581-3r and better defined, but more difficult to prepare. The fundamental properties (both chemical and biological) of dendrimers are described. Dendritic chain reaction (DCR), a signal amplification technique that uses the disassembly properties of self-immolative dendrimers is also mentioned.

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https://doi.org/10.1007/978-3-642-97572-1nd purified by separation methods, as well as, they can be employed as stationary phase and/or selection factors improving the efficacy of separation techniques. The two main classes of separation techniques are chromatographic and electromigration methods. Even combination of two complementary tech

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https://doi.org/10.1007/978-3-642-60749-3ication of new drugs. The production of DCL in the presence of a target creates a library of compounds skewed toward structures that interact favorably with that target. The topic of dynamic combinatorial chemistry as a tool for the design of functional materials and devices with new properties is v

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https://doi.org/10.1007/978-3-642-97944-6 as nontoxic or biocompatible. Clinical experience with dendrimers is still in its infancy; therefore, it is impossible to specify any chemistry insistingly biocompatible or toxic. Coating of nanomaterials with glycodendrimers results in formation of biocompatible nanoparticles such as solid lipid n

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https://doi.org/10.1007/978-3-642-97944-6eceptors. Their diameter in the range of 1–100 nm corresponds to molecular mass in the interval 10.–10. Da and a number of atoms within 10.–10. atoms. These nanodimensions allowed nanoscale systems to act both on the cell surface and in inner parts of cells. Therefore, nanoscale systems can detect d

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