Titlebook: Biomedical Advances in Aging; Allan L. Goldstein Conference proceedings 1990 Plenum Press, New York 1990 Alzheimer.aging.dementia.senescen

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Polyenoic Fatty Acid Metabolism and Prostaglandin Biosynthesis in Aged Personsged persons the incorporation of linoleic acid into plasma lipids. By measuring the elongation product, arachidonic acid, we were able to estimate the activity of the rate-limiting enzyme in this process, the delta-6-desaturase. Finally, we monitored PG formation by measuring the joint urinary metabolite of PGE, PGF, and PGD in 24-hr urine.

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Brain Amyloidosesic and axonal processes and cell bodies of neurons and, to a lesser extent, in astrocytes and oligodendrocytes; an extensive astroglial hypertrophy and proliferation; and spongiform change or status spongiosis of gray matter and extensive neuronal loss (Beck .., 1975, 1982; Klatzo .., 1959).

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n, D.C., attracted over three hun­ dred fifty scientists from twenty-five countries. The leading scientific experts in the field reported on recent biomedical advances in aging. They provided an up-to-date account of the molecular, genetic, nutritional, and immunological mechanisms associated with t

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Evidence for the Molecular Basis of Aging and Sequestration of Mammalian Erythrocytesd that RBC have a definite life span in the circulation. He accomplished this by the transfusion of RBC of blood group O into individuals of blood types A or B. He noted that, despite the compatibility of the blood transfusion, the RBC did not survive indefinitely. His data suggested an average life span of 83 days.

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