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Titlebook: Biomechanics: Trends in Modeling and Simulation; Gerhard A. Holzapfel,Ray W. Ogden Book 2017 Springer International Publishing Switzerland

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期刊全称Biomechanics: Trends in Modeling and Simulation
影响因子2023Gerhard A. Holzapfel,Ray W. Ogden
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发行地址Presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues.Particular attention is focused on microstructural and multi-scale modeli
学科分类Studies in Mechanobiology, Tissue Engineering and Biomaterials
图书封面Titlebook: Biomechanics: Trends in Modeling and Simulation;  Gerhard A. Holzapfel,Ray W. Ogden Book 2017 Springer International Publishing Switzerland
影响因子The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues..The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with anemphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose
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978-3-319-82364-5Springer International Publishing Switzerland 2017
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,Was ist an Intelligenz künstlich?, as applied to biphasic mixtures consisting of a porous-permeable deformable solid matrix and an interstitial fluid. Canonical problems of permeation, confined compression, and unconfined compression are analyzed from theory and compared to prior experimental measurements on articular cartilage, wit
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https://doi.org/10.1007/978-3-7985-1831-5astic properties of soft biological tissues. In particular, it highlights methods for including the fibrous structure of such tissues within the constitutive description of the material properties at the macroscopic level. Of particular relevance in this connection are the so-called preferred direct
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,Das künstliche Kniegelenk: Kurz und knapp, arrangement of the collagen fibers alters due to diseases such as aneurysms. We review a general dispersion model that is required to describe the mechanical response of a variety of collagenous tissues such as aortic walls considering three structural and three material parameters. The dispersion
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https://doi.org/10.1007/978-3-7985-1831-5ue, where fundamental constitutive representations, tissue anisotropy, tissue remodeling and damage modeling are overviewed. The focus then shifts to diseased tissue (atherosclerotic plaque tissue), where experimental mechanical characterization, and constitutive and damage modeling are reviewed. Co
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https://doi.org/10.1007/978-3-7985-1831-5rks of macromolecular fibers, especially collagen fibers, has been recognized, but models at any scale that explicitly incorporate fiber-fiber interactions into a mechanical description of the tissue have only started to emerge more recently. The purpose of this chapter is to provide the reader with
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