Titlebook: Biomechanics of Cells and Tissues; Experiments, Models Paola Lecca Book 2013 Springer Science+Business Media Dordrecht 2013 biological pro

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Book 2013function of living systems..The contributions presented in this book are current research highlights of six challenging and representative applicative domains of phyisical, engineering, and computational approaches in medicine and biology, i.e tissue engineering, modelling of molecular structures, c

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Computer-Aided Tissue Engineering: Application to the Case of Anterior Cruciate Ligament Repair,id-co-(.-caprolactone)) (PLCL) fibers arranged into a multilayer braided structure will be assessed using dedicated numerical tools. Preliminary biological assessments are also presented, and some conclusions concerning the suitability of the scaffold and the interest of CATE in this case will be dr

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A Model Predicting Rolling Cells Percentage in Inflamed Brain Venules,nd activation factors. The biochemical stochastic .-calculus is an efficient tool for describing the concurrency of the different interactions driving the phases of lymphocytes recruitment. It models a biochemical systems as a set of concurrent processes selected according to a suitable probability

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Analysis and Modeling of Metabolism of Cancer, metabolic phenotype of cancer provides an interesting avenue for diagnosis and treatment and several examples of such applications are already in place. Novel methods for metabolic profiling, comprised under the term metabolomics, provide tools for collection of data on cancer cell and tissue’s met

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Modelling the Influence of Cell Signaling on the Dynamics of Gene Regulatory Networks,of individual cells, with particular regard on their variety and homeostasis. The main results described in this chapter show that both the diversity of emergent behaviors and the diffusion of perturbations may not depend linearly on the fraction of genes involved in the signaling network. On the co

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Mechanistic Models of Astrocytic Glucose Metabolism Calibrated on PET Images,he astrocytic glucose use (i.e. glutamate, glucose, ., .-threohydroxyaspartate) and the dynamical rates of glutamate, glucose and . uptake. The second model includes also the effects of inter-cellular waves of . and . generated by astrocytes on the glucose metabolism. The kinetic rates constants of

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Cisterna cerebellomedullaris und Inhalterwise challenging structures can be modeled. In these models the complexity of the structures are incrementally increased with respect to the biological data. We present a geometric representation of these models that we use to generate movies reflecting their dynamics while preserving formal cleanliness as well as loyalty to the biological data.