Titlebook: Biomechanics in Oncology; Cheng Dong,Nastaran Zahir,Konstantinos Konstantopo Book 2018 Springer Nature Switzerland AG 2018 Biomaterials in

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https://doi.org/10.1007/978-3-8349-9946-7 monolayer in single, multi-cell chain and collective modes. Using a mismatch of fiber diameters, we describe a new method to . single protrusions and describe migratory behavior of cells in different shapes. Altogether, control over fiber geometry and network architecture enables the STEP platform

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Leistung und Grenzen bestehender CT-Modelle,tors and intracellular mechanics are expected to play an integral role in cancer progression and treatment success. Brillouin confocal microscopy is appealing for many studies in cancer mechanobiology involving both primary tumors and metastatic dissemination. Specifically, Brillouin technology is s

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Biomechanics in Oncology978-3-319-95294-9Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Zusammenfassung der Ergebnisse und Ausblick,l observations have been corroborated by the precise measurement and characterization of mechanical properties of cancerous tissues. Much of the advancement in our understanding of mechanics in oncology has been enabled by the development of innovative technologies designed to probe cells and tissue

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https://doi.org/10.1007/978-3-8350-9041-5 the double helix as revealed by single-molecule experiments will be described, with an emphasis on the role of polymer statistical mechanics. We will then discuss how topological constraints— entanglement and supercoiling—impact physical and mechanical responses. Models for protein–DNA interactions

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Zusammenfassung der Ergebnisse und Ausblick, cancer, abnormal signaling leads to stiffening of the ECM. A stiff microenvironment affects many aspects of the cell, including internal molecular signaling as well as behaviors such as motility and proliferation. Thus, cells and ECM interact in a feedback loop to drive matrix deposition and cross-