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Titlebook: Biomaterials in Regenerative Medicine and the Immune System; Laura Santambrogio Book 2015 Springer International Publishing Switzerland 20

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Targeting Liposomes to Immune Cells, modify antigen-specific T cell responses and provides a strategy for enhancing vaccines which require potent T cell responses. Furthermore, in the absence of adjuvant delivery of antigen to DCs induces antigen-specific T cell anergy, providing a potential method for treating autoimmune diseases. En
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Integrated Biomaterial Composites for Accelerated Wound Healing,currently under research and in clinical practice. Given the inflamed, open, and moist nature of wounds, the damaged dermal layers are exposed both to internal (inflammatory cytokines) and external (infection) factors requiring immediate localized intervention which can provide therapeutic action an
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Adverse Effects of By-products from Polymers Used for Joint Replacement,ly used in TJRs. Fortunately, most TJRs last for decades. However, excessive use of the TJR and impact-loading activities are generally prohibited due to potential fracture and degradation of the cement mantle and excessive wear of the polyethylene-articulating surface. Polymer wear particles and by
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Book 2015polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components.  As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.. .
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,Versuchsdurchführung und Ergebnisse,M2), and the role it plays in wound healing and biomaterial vascularization. We conclude with a discussion of biomaterial design strategies that have been suggested to positively interact with and potentially control macrophages in order to improve interactions with the inflammatory response.
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https://doi.org/10.1007/978-3-642-47865-9affold to choose for the goal tissue to be regenerated. By combining the optimum regenerative immune environment with the innate polarization tendencies of scaffolds, we will be better able to cater specific scaffolds to their applications and improve clinical outcomes.
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https://doi.org/10.1007/978-3-322-95241-7rfaces while maintaining bacteriophage’s biological activities capable of killing deadly human pathogens are also explored. This alternative approach of fighting microbial wars on polymeric surfaces may be considered as a long-term alternative to inhibit early stages of microbial film formation.
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Bezugsrahmen des Projektcontrolling,teria. We describe several types of these coatings, which can carry high payloads of antimicrobials but do not release them at normal physiological conditions at pH 7.5 until the arrival of a bacterial trigger. Importantly, these coatings inhibit bacterial colonization while simultaneously promoting a healthy tissue response.
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