Titlebook: Biomaterials Associated Infection; Immunological Aspect T. Fintan Moriarty,Sebastian A.J. Zaat,Henk J. Bus Book 2013 Springer Science+Busin

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Antimicrobial Medical Devices in Preclinical Development and Clinical Useecome progressively more complex to accommodate diverse demands for performance and safety in vivo. While a majority of these implants satisfy their clinical expectations with safety and efficacy in their specific applications, a minority of implants induce serious adverse events with substantial he

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Quaternary Ammonium Compoundstheaters from bacteria, as human bodies contain already 10. bacteria. Once on a surface, bacteria start proliferating, while protecting themselves with a slime layer against the immune system and administered antibiotics. A promising route to prevent or at least reduce bacterial infections caused by

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Anti-adhesive and Antibacterial Polymer Brushes of the device surface with a dense layer of polymer chains which can resist bacterial adhesion and colonization. These polymer chains may present large exclusion volumes to inhibit protein and bacterial adhesion and/or possess ­bactericidal functional groups. The coating of surfaces with these poly

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T. Fintan Moriarty,Sebastian A.J. Zaat,Henk J. BusProvides a clinical perspective to set research directions.Summarizes the pathogenicity of the most common bacterial species isolated in BAI.Covers both biofilms and tissue reservoirs as modes of infe

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978-1-4899-9374-8Springer Science+Business Media New York 2013