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Titlebook: Biomarkers in Bone Disease; Vinood B. Patel,Victor R. Preedy Reference work 2017 Springer Science+Business Media Dordrecht 2017 Applicatio

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Utilization and Reference Values of Bone Turnover Markers: Osteocalcin and Procollagen Type 1 N-Prop bone tissue are accompanied by changes of biochemical markers. Plasma (and/or urine) concentration of these markers depends on bone resorption/formation activity, i.e., bone turnover rate. Osteocalcin is important noncollagenous protein in bone matrix, synthetized by osteoblasts and osteocytes. It
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Pentraxin 3 (PTX3) as a Biomarker of Bone Disease of cells in response to proinflammatory signals and Toll-like receptor engagement. Albeit the protective functions of PTX3 in several infection, the persistent elevation in PTX3 levels is associated with disease severity and increased morbidity in diverse clinical pathological conditions such as ps
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Hormone Relaxin as Biomarker for Bone Health and Diseasemetabolism-related biomarkers such as a soluble factor or type I collagen metabolism product specifically secreted by osteoblasts or osteoclasts are useful for evaluating the change in bone metabolism in a noninvasive manner in real time. Monitoring of bone metabolism-related biomarkers that are exc
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Vitamin D: Biological Significance and Diagnosis of Mild Deficiencyg both bone formation and resorption. This last effect may be mainly indirect by modulating PTH secretion. In mild forms of vitamin D deficiency, the increase in PTH secretion is probably the main factor determining bone loss..In diagnosis of vitamin D deficiency, the establishment of a circulating
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https://doi.org/10.1007/978-94-007-7693-7Application to prognosis; Biomarkers in disease; Cancer Research; Discovery of biomarkers; High throughp
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