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Titlebook: Biomarkers for Alzheimer’s Disease Drug Development; Robert Perneczky Book 2024Latest edition The Editor(s) (if applicable) and The Author

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发表于 2025-3-21 19:35:02 | 显示全部楼层 |阅读模式
期刊全称Biomarkers for Alzheimer’s Disease Drug Development
影响因子2023Robert Perneczky
视频video
发行地址Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts
学科分类Methods in Molecular Biology
图书封面Titlebook: Biomarkers for Alzheimer’s Disease Drug Development;  Robert Perneczky Book 2024Latest edition The Editor(s) (if applicable) and The Author
影响因子This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies helping to accelerate Alzheimer’s disease drug development. Addressing the latest advances in preclinical and clinical research, including new insights into the molecular mechanisms and emerging therapeutic strategies, the book continues by exploring digital biomarkers and advanced neuroimaging analysis which will transform how clinical trials in the Alzheimer’s disease field are performed. Written for the highly successful .Methods in Molecular Biology. series, chapters feature the kind of detailed implementation advice that leads to greater success in the lab or clinic. .Authoritative and practical, .Biomarkers for Alzheimer’s Disease Drug Development, Second Edition. seeks to inspire and inform future efforts to develop effective treatments for this devastating disease..
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发表于 2025-3-21 20:25:42 | 显示全部楼层
https://doi.org/10.1007/978-3-531-90385-9have slightly modified the methodology, increasing the glycosylation time and using a high-resolution mass analyzer for the analysis of CSF .-glycans, thus obtaining a high-throughput method (up to 96 samples simultaneously), mass accuracy better than 5 ppm, and the ability to separate and identify isomers.
发表于 2025-3-22 01:54:51 | 显示全部楼层
https://doi.org/10.1007/978-3-531-90385-9graphy and gas chromatography. These procedures have been optimized for the analysis of multiple biological samples from human patients and transgenic animal models, including blood serum, various brain regions (e.g., hippocampus, cortex, cerebellum, striatum, olfactory bulbs), and other peripheral organs (e.g., liver, kidney, spleen, thymus).
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发表于 2025-3-22 12:40:36 | 显示全部楼层
Konfliktbearbeitung durch den Europaraterges as a synergistic approach to understand the structural correlates related with specific AD-related biomarkers. In this chapter, we describe the methods used in neuroimaging that will allow researchers to combine data on CSF metabolites with imaging analyses.
发表于 2025-3-22 13:54:26 | 显示全部楼层
https://doi.org/10.1007/978-3-663-08073-2erpreted by means of visual/qualitative, semiquantitative, and quantitative criteria. Here, we summarize the main differences between the available radiotracers for Amy-PET, the proposed interpretation criteria, and main proposed quantification methods.
发表于 2025-3-22 18:03:09 | 显示全部楼层
发表于 2025-3-23 00:23:06 | 显示全部楼层
Book 2024Latest edition kind of detailed implementation advice that leads to greater success in the lab or clinic. .Authoritative and practical, .Biomarkers for Alzheimer’s Disease Drug Development, Second Edition. seeks to inspire and inform future efforts to develop effective treatments for this devastating disease..
发表于 2025-3-23 04:21:45 | 显示全部楼层
https://doi.org/10.1007/978-3-531-90385-9has been optimized to obtain high-quality mass spectra in reflector mode with an optimal signal-to-noise ratio up to . 4800. This method has been successfully adopted to associate specific N-glycome profiles to the early and the advanced phases of Alzheimer’s disease (AD).
发表于 2025-3-23 07:33:39 | 显示全部楼层
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