Titlebook: Biomarker Methods in Drug Discovery and Development; Feng Wang Book 2008 Humana Press 2008 Clinical sample handling.DNA.Drug efficacy and

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Sandwich ELISA Microarrays: ,,ltiple proteins in a miniaturized assay. The technical challenges of generating and processing the arrays are numerous. However, careful attention to possible pitfalls in the development of one’s antibody microarray assay can overcome these challenges. In this chapter, we describe in detail the step

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GC-MS-Based Metabolomics,e 1980s. Only during the past few years has the technology been more widely used for metabolomics studies in animals and humans with the aim of toxicology and biomarker discovery, disease diagnosis and classification..GC-MS is ideally suited and has traditionally been used for analysis of nonpolar a

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NMR-Based Metabolomics for Biomarker Discovery,arly disease detection, patient stratification for treatment, and information on disease processes. With its ability to discover new metabolic markers, metabolomics (as well as metabolic profiling and metabonomics) is highly effective for drug development by providing early preclinical indications o

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1557-2153 ndous urgency to address this question. Biomarkers also fit perfectly with the vision of personalized medicine, the new expectation of medical practice. This is why biomarker research has been a central focus i978-1-61737-925-3978-1-59745-463-6Series ISSN 1557-2153 Series E-ISSN 1940-6053

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Softwarestruktur eines Funktionsblocks,). LCM is a new technology that has substantially expanded our ability to examine cell-type–specific and region-specific responses in complex cellular tissues. Importantly, this technique allows the retrieval of specific cells from specific morphologic units within the tissue of interest..The primat