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Titlebook: Biology of the Arterial Wall; Bernard I. Levy,Alain Tedgui Book 1999 Springer Science+Business Media New York 1999 blood vessel.cells.endo

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发表于 2025-3-21 17:58:45 | 显示全部楼层 |阅读模式
期刊全称Biology of the Arterial Wall
影响因子2023Bernard I. Levy,Alain Tedgui
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学科分类Basic Science for the Cardiologist
图书封面Titlebook: Biology of the Arterial Wall;  Bernard I. Levy,Alain Tedgui Book 1999 Springer Science+Business Media New York 1999 blood vessel.cells.endo
影响因子.Biology of the Arterial Wall. is intended as a generalreference text concerned with the biology of the vascular cells andthe blood vessel wall under physiological and pathological conditions.One of the major functions of the arteries is to maintain a continuousblood flow to the organs whatever the pressure conditions, thanks tothe vasomotor tone of the smooth muscle cells. Great advances havebeen made over the last decade in the understanding of the endothelialcells as integrators and transducers of signals originating from theblood stream. The pluripotent control functions of the endothelialcells in the vessel wall are now well recognized. A review ofendothelial functions and dysfunctions is presented. .Cell biology and molecular genetic studies have now identified anarray of molecules elaborated by endothelial cells and vascular smoothmuscle cells and by the blood-borne elements which interact withartery cells, defending the artery against injury and modulatingevolving abnormal processes. Molecules which induce or inhibitendothelial and/or smooth muscle cells are currently under greatscrutiny. Angiogenesis, which plays a major role in tumor growth, butmay also be beneficial as a
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Neurohumoral Control of the Vascular Systemomotor alterations and participates in the control of the internal environment and homeostasis. The vascular smooth muscle is the effector organ for these alterations. Indeed, with the exception of capillaries and some venules, the vessels have the ability to alter their calibre, to influence the re
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Endothelial Function and Dysfunctionion and proliferation of vascular smooth muscle, adhesion of leucocytes and platelets, permeability and inflammatory responses. The endothelium also possesses thrombolytic and fibrinolytic properties. In addition, its metabolic activity regulates the oxidation of plasma lipids, the formation of angi
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Angiogenic Growth Factorsogenesis is described as a primary in situ differentiation of endothelial cells from mesodermal precursors, leading to the formation of primary capillary poleaxe. Angiogenesis was thought to be exclusively the result of vessels’ sprouting from pre-existing vessels. But recently, Asahara et al. have
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Vascular Agingg is associated with large artery remodeling, characterized by a progressive increase in stiffness and changes in the function of the endothelium and of smooth muscle cells (SMC). The effects of aging on the arterial system should be differentiated from that of atherosclerosis. Even though atheroscl
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Apoptosis in Normal and Pathological Vessels[., .] or during normal aging . in the absence of overt necrosis. Rational explanations for these observations may now be at hand after the description by Kerr and colleagues in the early 1970s of a novel form of cell death distinct from necrosis, which they designated “apoptosis” (from the Greek wo
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