Titlebook: Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics; Yoshihiro Kawaoka Book 2004 The Editor(s) (if applicable) and The A

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0070-217X of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control. .978-3-642-07375-5978-3-662-06099-5Series ISSN 0070-217X Series E-ISSN 2196-9965

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Totale Lungenvenenfehleinmündungan one pathogen. Finally, recombinant viruses that selectively enter cells expressing tumor markers or the HIV envelope protein have been engineered and shown to lyse target cells. Preclinical and clinical trials of improved and multivalent vaccines and therapeutic (oncolytic) viruses are ongoing.

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Book 2004ume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further p

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Reverse Genetics Systems for the Generation of Segmented Negative-Sense RNA Viruses Entirely from C reverse genetics of segmented negative-sense RNA viruses, beginning with the in vitro reconstitution of viral polymerase complexes in the late 1980s and culminating in the generation of Bunyamwera and influenza virus entirely from plasmid DNA almost a decade later.

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Toward Novel Vaccines and Therapies Based on Negative-Strand RNA Viruses,an one pathogen. Finally, recombinant viruses that selectively enter cells expressing tumor markers or the HIV envelope protein have been engineered and shown to lyse target cells. Preclinical and clinical trials of improved and multivalent vaccines and therapeutic (oncolytic) viruses are ongoing.

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Reverse Genetics of ,,ols to study all aspects of the virus life cycle as well as the roles of virus proteins in virus-host interplay and pathogenicity. In addition, recombinant viruses can be designed to have specific properties that make them attractive as biotechnological tools and live vaccines.

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