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Titlebook: Biology of Endothelial Cells; Eric A. Jaffe Book 1984 Martinus Nijhoff Publishers, Boston 1984 Lipoprotein.angiogenesis.arteries.artery.bi

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期刊全称Biology of Endothelial Cells
影响因子2023Eric A. Jaffe
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学科分类Developments in Cardiovascular Medicine
图书封面Titlebook: Biology of Endothelial Cells;  Eric A. Jaffe Book 1984 Martinus Nijhoff Publishers, Boston 1984 Lipoprotein.angiogenesis.arteries.artery.bi
影响因子The participation of endothelial cells in various physiologic and pathologic processes has been hypothesized since before the turn of the century. However, until recently, direct evidence for endothelial involvement in these processes has been extremely difficult to obtain due to the inability to study endothelial cell function in vitro. Though the possibility of using cultured endothelial cells to study endothelial cell function in vitro was recognized many years ago, the inability to culture unambiguously identifiable endothelial cells limited investigators in their studies of endothelial function. As a result, the field of endothelial cell biology lay relatively fallow for many years. The development in the early 1970‘s of routine and easily implemented methods for culturing human endothelial cells and the demonstration that cultured endothelial cells synthesized a physiologically relevant protein, Factor VIII/von Willebrand Factor, quickly changed this state of affairs. Over the following decade the scope of endothelial cell research rapidly widened, spreading in a number of directions. First, methods were developed to culture endothelial cells from a variety of species. Second
Pindex Book 1984
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https://doi.org/10.1007/978-3-658-08742-5scular cells as being endothelium (6). In contrast to 3T3 cells and other cells exhibiting density inhibition of growth, the addition of fresh serum or of any of the known growth factors does not influence this monolayer pattern of cultured endothelium in its stationary, post-confluent phase of . gr
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https://doi.org/10.1007/978-3-658-08742-5y 10. times from large vessels to capillaries. It follows from the law of mass action that the occupancy of possible binding sites — and hence the fate of circulating substances — may change dramatically in the capillaries.
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