Titlebook: Biology of Amphibian Tumors; Merle Mizell Book 1969 Springer-Verlag New York Inc. 1969 biology.cancer.cancer research.carcinogenesis.carci

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Birgit Oberer,Alptekin Erkollary. Thus, 3 6 distinct lines are at present maintained in frozen storage or continuous culture. Our purpose in this paper is to describe how such lines are initiated, the morphological changes which the cells undergo, their chromosome constitution, and their properties as experimental material. We wi

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Mass Culture of Amphibian Cells: Methods and Observations Concerning Stability of Cell Typesuccess in maintaining monolayer strains through serial subculture. The first permanent amphibian line is that of Wolfe and Quimby (27), derived from bullfrog tongue. This line subsequently proved to be fibroblastic in morphology and subtetraploid in chromosome number. To date, it has passed through

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Dependence of Tumor Formation in Frogs on Abnormal Nucleolar Functions lead, chromium, and cobalt were begun. Heavy metals were found capable of stimulating nucleolar organizers and initiating adenocarcinomas in the kidney, with comparable pathology of the lung, liver, and occasionally spleen. Thus, in effect, it was found possible to induce in the frog kidney a so-c