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Titlebook: Biology of Aging and Development; G. Jeanette Thorbecke Book 1975 Springer Science+Business Media New York 1975 aging.biology.cancer.devel

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Growth and death of diploid and transformed human fibroblaststransformed lines: .) Only diploid cells have a molecular clock mechanism which counts cell divisions prior to senescence. Two hypothetical examples of such mechanisms are described; however, the available evidence argues against a clock mechanism for aging in fibroblasts. .) Cells become committed
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Pathological implications of cell aging in vitroteractions with polymerizing fibrin. The replicative capacity of cells is diminished in diabetes mellitus and certain related disorders such as progeria and Werner’s syndrome, all of which feature accelerated aging. Expression of HL-A antigens is reduced in progeria fibroblasts compared to normal cu
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Age-related changes in thermoregulatory capacity of tryptophan-deficient rats aging and old rat subjected to 3 minutes of whole-body ice water immersion, and .) using this index of physiological age, to determine whether tryptophan deficiency from time of weaning can retard the onset of senescence. Results indicate a progressive prolongation of temperature recovery time from
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