Titlebook: Biology and Therapy of Acute Leukemia; Proceedings of the S Laurence Baker,Frederick Valeriote,Voravit Ratanat Conference proceedings 1985

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书目名称Biology and Therapy of Acute Leukemia影响因子(影响力)




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Beratung im Kontext lebenslangen Lernens, leukemia cells derived from Abelson virus (A-MuLV) leukemic mice and interleukin-3 dependent hemopoietic cells infected . with A-MuLV. All promonocytic cell lines cloned from A-MuLV leukemic mice were growth factor independent . and tumorigeneic .. Separate, cloned lines from individual leukemic mi

破布

Beratung im Kontext lebenslangen Lernens,synthesis or with the metabolism of other cell components lack selective antitumor activity. If cytotoxicity, which forms the basis for current treatment regimens, were the major determinant for selective antitumor action, then inhibitors of cellular targets other than DNA should have emerged as cli

等级的上升

Gerhard Schewe,Ann-Marie NienaberIn many of the subsequent studies over the next decade, single agents were used to induce a remission and therapy was then stopped until there was recurrence of the disease (Table I). The most effective single agents were prednisone and vincristine which induced remission in 60% to 70% of the childr

持续

epidermis

Gerhard Schewe,Ann-Marie Nienaberde a historical perspective on the emergence of modern chemotherapy against ANLL. By reviewing past and current clinical trials, an appreciation of the stepwise progress which has been made in the understanding and management of this disease may be gained.