Titlebook: Biology and Management of Unusual Plasma Cell Dyscrasias; Todd M. Zimmerman,Shaji K. Kumar Book 2017 Springer Science+Business Media New Y

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,Plasmacytoma—Current Approach to Diagnosis and Management,ogical symptoms from spinal cord compression. The role of adjuvant RT after complete surgical resection, adjuvant chemotherapy, or adjuvant bisphosphonates is not well defined and hence not recommended.

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Immunoglobulin Deposition Diseases,drugs, proteasome inhibitors, and with autologous stem cell transplantation. In this review, we address clinical presentation and outcomes with light-chain and heavy-chain monoclonal immunoglobulin deposition disease, Type I cryoglobulinemia, proliferative glomerulonephritis with monoclonal IgG depo

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Idiopathic Systemic Capillary Leak Syndrome (Clarkson Disease),isorder, there remains a paucity of high-level evidence, particularly with regard to efficacy of the currently available therapies. This chapter outlines the diagnostic dilemmas and current approaches related to the management of idiopathic SCLS.

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,Plasmacytoma—Current Approach to Diagnosis and Management,al plasma cells without evidence of bone marrow involvement or end-organ damage known as a solitary plasmacytoma (SP). SP of bone mostly occurs in axial skeleton, while it most often affects the head and neck region in case of extramedullary tumors. Their median age is 55 years and mostly present wi

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Light Chain Amyloidosis,linical presentation. Prognosis of AL amyloidosis depends on organ, particularly cardiac, involvement. Treatment of AL amyloidosis includes chemotherapy using alkylators, novel therapies and autologous hematopoietic cell transplantation. Amyloid fibril-directed therapy is currently lacking. In this

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