Titlebook: Biology and Control Theory: Current Challenges; Isabelle Queinnec,Sophie Tarbouriech,Silviu-Iulian Book 2007 Springer-Verlag Berlin Heidel

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Piecewise-Linear Models of Genetic Regulatory Networks: Theory and Examplely of such models and analysis methods enabling us to better understand the dynamics of genetic regulatory networks. We apply such methods to the network that underlies the nutritional stress response of the bacterium ..

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Direct Adaptive Control of Nonnegative and Compartmental Dynamical Systems with Time Delayorthant in the presence of unknown system time delay. The framework additionally guarantees nonnegativity of the control signal. Finally, we demonstrate the framework on a drug delivery model for general anesthesia involving system time delays.

初学者

Bert Bielefeld,Peter J. Fröhlichy function giving an age and maturity-structured description of its cell population. The control intervenes in the velocity and loss terms of the conservation law ruling the changes in the density. This leads to some new control problems.

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https://doi.org/10.1007/978-3-211-69393-3xis for the single and multiple discrete (constant) delays or for some particular classes of distributed delays (gamma-distribution with a gap). Several examples (human respiration, cell-to-cell spread models in well-mixed configurations or immune dynamics in chronic leukemia) complete the presentation.

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Analysis and Control of Dynamical Biological Systems in Presence of Limitations

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Mini-Transplants for Chronic Myelogenous Leukemia: A Modeling Perspectived prior to the transplant, a procedure known as a mini-transplant. Our results suggest that mini-transplants may be advantageous over full transplants. We identify the regions of the parameters for which mini-transplants are advantageous using statistical tools.

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