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Titlebook: Biologics in General Medicine; Wolf-Henning Boehncke,Heinfried H. Radeke Book 2007 Springer-Verlag Berlin Heidelberg 2007 Arthritis.Monito

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发表于 2025-3-21 19:50:56 | 显示全部楼层 |阅读模式
期刊全称Biologics in General Medicine
影响因子2023Wolf-Henning Boehncke,Heinfried H. Radeke
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发行地址First comprehensive book on the new drug generation of biologicals.Contains all biologicals presently approved for clinical application.Covers all aspects from the biotechnological production processe
图书封面Titlebook: Biologics in General Medicine;  Wolf-Henning Boehncke,Heinfried H. Radeke Book 2007 Springer-Verlag Berlin Heidelberg 2007 Arthritis.Monito
影响因子The idea for this book was born during the symposium on biologics organized by ZAFES (Center for Drug Research, Development and Safety at the University of Frankfurt am Main) in September 2005. Highly distinguished researchers special- ing in the field of biologics had gathered together to exchange information on this relatively new subject. Realizing that this symposium was one of the few sources of condensed information on biologics, it became obvious that we had to create a means of informing an interested wider circle of scientists and especially general c- nicians. Therefore, the editors of this book suggested to the researchers at the symposium andalsotoprominent scientists andcliniciansinvolvedinthe developmentand application of biologics as their major field of interest the idea of assembling this compendium. We received an overwhelmingly positive response – thankfully also from the publisher – most being more than willing to support this innovative project with highly relevant chapters on the latest state of the art. As we were eager to fill the information gap with up-to-date knowledge, the project had to be finished within the shortest time possible. To all experienced w
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Infliximab: From the Idea to the Productle and membrane- bound TNF-α . Infliximab does not bind to TNF-β (lymphotoxin α ), a related cytokine that utilizes the same receptors as TNF-α. Thus infliximab was developed as a therapeutic agent for various inflammatory chronic diseases that are believed to be driven by the pro-inflammatory cytok
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The Production of Biopharmaceuticals chemical synthesis, biologics are made by biosynthesis in living cells. Biologics are generally much larger than traditional synthetic medicinal products and range from highly complex inactivated vaccines and plasma-derived factors to highly purified, well characterised recombinant therapeutic prot
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Treating Autoimmune Bullous Skin Disorders with Biologicsng distinct adhesionmolecules of the epidermis and dermoepidermal basement membrane zone leading to a loss of adhesive function of the target antigen(s) (Fig. 8.1). The appearance of blisters and erosions of the skin and/or mucous membranes is the leading clinical sign of autoimmune bullous skin dis
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Biologics in Psoriasisune mediated inflammatory changes seen in psoriasis have been elucidated, leading to the development of biologics that specifically act on immunological mechanisms, which are thought to be pathogenic in psoriatic lesions. By acting on specific immunological actions in the large cascade that results
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Biologic Agents in Psoriatic Arthritisof the population, although estimates of its prevalence vary widely, and is generally considered an autoimmune disease with unknown antigenic determinants. There currently is no predictive marker indicating which psoriasis patients will develop arthritis (Mease 2004). PsA often is classified as a su
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