Titlebook: Biological Signal Transduction; Elliott M. Ross,Karel W. A. Wirtz Conference proceedings 1991 Springer-Verlag Berlin Heidelberg 1991 G-Pro

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Mechanisms Underlying Hormonal Modification of Dopamine Receptor Sensitivityated. In these experiments we have used an animal model, the hypothyroid rat, which exhibits increased behavioural sensitivity to dopamine receptor agonists compared to euthyroid controls (Cameron & Crocker, 1990b).

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Biological Signal Transduction978-3-642-75136-3Series ISSN 1010-8793

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1010-8793 Overview: 978-3-642-75138-7978-3-642-75136-3Series ISSN 1010-8793

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https://doi.org/10.1007/978-3-642-55902-0rated to yield appropriate intracellular signals in the form of second messengers, such as cyclic AMP, inositol phosphates, Ca., . Although receptors are responsible for detecting extracellular signals, signal integration and sorting frequently depend on the activities of GTP-binding transducer proteins known as G proteins.

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https://doi.org/10.1007/978-3-642-55902-0(Gautvik et al. 1988). Recently, we have been interested in the coupling of pituitary peptide hormone receptors to specific GTP-binding regulatory proteins (G proteins) and how these signal proteins initiate intracellular messenger effector systems.

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Hirnelektrische Grundlagen der Hypnosen one pathway activation of G-proteins and adenylate cyclase produces the second massenger cAMP, while in the other pathway a rapid turnover of phospholipids generates two second messangers IP3 and diacylglycerol (for review Berrdige, 1987).